Non-alcoholic Fatty Liver Disease and Glucose Metabolism in Obese Children

Background Type 2 diabetes mellitus (T2DM) accounts for the majority of diabetes over widespread ages from childhood to adulthood. Those affected have similar characteristics, such as excessive abdominal body fat, extreme insulin resistance (decreased responsiveness to insulin), and problems with beta-cell function, which are the cells that produce insulin. Another risk factor of obesity is […]

Greater Weight Loss and Insulin Sensitivity with Carbohydrates Eaten Mostly at Dinner

Background Body fat has the ability to secrete certain hormones throughout the day which can regulate hunger, satiety, and the development of metabolic syndrome. Among the hormones secreted by body fat, leptin and adiponectin are involved in satiety and improving insulin sensitivity, respectively. Both can possibly be modified through altered carbohydrate consumption in order to […]

Effects of 4 Weight-loss Diets Differing in Fat, Protein, and Carbohydrate on Fat Mass, Lean Mass, Visceral Adipose Tissue, and Hepatic Fat: Results from the Pounds Lost Trial

Background The problem is that there are currently many fad diets and diet supplements that claim to change total body weight and waist circumference. However, the aim of any weight loss attempt is the reduction of fat mass rather than lean mass. The standard measurement for overall body weight change gives total mass lost with […]